Chlorthalidone/ clonidine is used for:
Treating high blood pressure. It may also be used for other conditions as determined by your doctor.
Chlorthalidone/clonidine is a combination alpha agonist and diuretic. The alpha agonist works by relaxing blood vessels and decreasing heart rate. The diuretic works by increasing elimination of sodium and water.
Do NOT use chlorthalidone/ clonidine if:
you are allergic to any ingredient in chlorthalidone/clonidine or to sulfonamide medicines (eg, sulfamethoxazole)
you are unable to urinate
Contact your doctor or health care provider right away if any of these apply to you.